Porous Poly(ε-Caprolactone) Scaffolds for Retinal Pigment Epithelium Transplantation
نویسندگان
چکیده
منابع مشابه
Retinal pigment epithelium-retina transplantation for retinal degenerative disease.
U N C O R R EC N THIS ISSUE OF THE JOURNAL, RADTKE AND ASSOCIates report on the results of a phase 2 clinical trial of fetal retinal pigment epithelium (RPE)–retina translantations in patients with retinitis pigmentosa (RP) and ge-related macular degeneration (AMD). Visual acuity VA) improved in seven of 10 study eyes and in three of 10 ellow control eyes. Some issues that merit consideration r...
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Antibody-mediated rejection is characterized by donor-specific antibody produced by B cells. However, to our knowledge, B cell invasion and antibody in the inflamed retina after transplantation of retinal pigment epithelial (RPE) cells has not been reported. To determine if RPE transplantation could be performed using allografts, we established in vivo immune rejection models with induced pluri...
متن کاملRetinal Pigment Epithelium–Retina Transplantation for Retin Degenerative Disease
s s t a v s s r s d p b c o N THIS ISSUE OF THE JOURNAL, RADTKE AND ASSOCIATES report on the results of a phase 2 clinical trial of fetal retinal pigment epithelium (RPE)–retina transplants in atients with retinitis pigmentosa (RP) and age-related maclar degeneration (AMD). Visual acuity (VA) improved in even of 10 study eyes and in three of 10 fellow control eyes. ome issues that merit conside...
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Introduction: Degenerative retinal diseases are main cause of irreversible blindness. Stem cells therapy is a promising way in these diseases. Therefore, mesenchymal stem cells because of its safety can produce degenerated cells and can play important role in treatment. The aim of this study was to examine morphological changes in injured retinal pigment epithelium (RPE) and photoreceptor cells...
متن کاملTransplantation of transduced retinal pigment epithelium in rats.
PURPOSE To examine the effects of transplanting retinal pigment epithelial (RPE) cells transduced with neurotrophic factor genes into the subretinal space of rats. METHODS RPE cells were transduced with plasmids carrying the cDNAs of Axokine (ciliary neurotrophic factor [CNTF]; Sumitomo Pharmaceuticals Co., Ltd., Tokyo, Japan), brain derived-neurotrophic factor (BDNF), and basic fibroblast gr...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2014
ISSN: 1552-5783
DOI: 10.1167/iovs.13-12833